Characteristic Features of a Case of Recurrent Neuroleptic Malignant Syndrome

AUTHORS

Aram Hamidi 1 , * , Smaneh Farnia 2 , Mehran Zarghami 2

1 Tehran Psychiatric Institute, Iran University of Medical Sciences. Shahid Mansoori Alley, Niayesh St., Sattarkhan Ave, Iran

2 Department of Psychiatry and Research Center for Psychiatry and Behavioral Sciences, Mazandaran University of Medical Sciences, Sari, Iran

How to Cite: Hamidi A, Farnia S, Zarghami M. Characteristic Features of a Case of Recurrent Neuroleptic Malignant Syndrome, Iran J Psychiatry Behav Sci. 2010 ; 4(2):61-3.

ARTICLE INFORMATION

Iranian Journal of Psychiatry and Behavioral Sciences: 4 (2); 61-3
Published Online: December 31, 2010
Article Type: Case Report
Received: March 12, 2009
Accepted: August 05, 2010

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Abstract

A 56-year old schizophrenic patient developed three episodes of Neuroleptic Malignant Syndrome (NMS) after age of 50. Patient was under treatment with risperidone and clozapine during the first two episodes respectively. But no antipsychotic was ever used during the 45-month period between 2nd and 3rd lethal episodes of NMS, and the patient was only treated with ECT, and promethazine as needed base. Patient used to show sub syndromal catatonia throughout this period. This might reflect a "trait vulnerability" to NMS which for full expression of the disorder need some sort of "state variable" such as a drug.

Declaration of interest: None.

Keywords

Catatonia Malignant Neuroleptics

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