Idiopathic Thrombocytopenia and Neurologic Manifestations in A Young Female Leading to the Diagnosis of Wilson’s disease

AUTHORS

Seyed Mohammad Salar Zaheryany 1 , Reza Bidaki 2 , * , Nahid Hemmatian Brujeni 1 , Mohammad Rezvani 1 , Mitra Hakim Shooshtari 1

1 Tehran University of Medical Sciences, Tehran, Iran

2 Rafsanjan University of Medical Sciences, Rafsanjan, Iran

How to Cite: Zaheryany S M S, Bidaki R , Hemmatian Brujeni N, Rezvani M, Hakim Shooshtari M. Idiopathic Thrombocytopenia and Neurologic Manifestations in A Young Female Leading to the Diagnosis of Wilson’s disease, Iran J Psychiatry Behav Sci. 2012 ; 6(2):99-6.

ARTICLE INFORMATION

Iranian Journal of Psychiatry and Behavioral Sciences: 6 (2); 99-6
Published Online: December 30, 2012
Article Type: Case Report
Received: August 27, 2011
Revised: August 02, 2012
Accepted: September 01, 2012

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Abstract

We present a 19-year-old patient with hematologic and neurologic manifestations associated with Wilson’s disease. Idiopathic thrombocytopenia was diagnosed in October 2009. Bone marrow aspiration was normal. Gradually her neurologic and psychiatric symptoms emerged, dysarthria, writing apraxia, learning difficulties, emotionalism and eventually dystonia of hands. The serum ceruloplasmin was low, and the Kayser Fleischer's ring was positive. MRI of the brain showed abnormality in the bilateral basal ganglia, brain stem and superior cerebellar peduncles without post-contrast enhancement.

Declaration of interest: None

Citation: Zaheryany SMS, Bidaki R, Hemmatian Brujeni N, Rezvani M, Hakim Shooshtari M, Idiopathic thrombocytopenia and neurologic manifestations in a young female leading to the diagnosis of Wilson’s disease. Iran J Psychiatry Behav Sci 2012; 6(2): 96-99

Keywords

Apraxia Kayser Fleischer's ring Thrombocytopenia Wilson’s disease

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